U.S. Route 23 (US 23) is a 157.765-mile-long (253.898 km) United States Numbered Highway in the state of Kentucky. It travels from the Virginia state line near Jenkins to the Ohio state line west of South Shore via Jenkins, Pikeville, Coal Run Village, Prestonsburg, Paintsville, Louisa, Catlettsburg, Ashland, Russell, Flatwoods, Raceland, Wurtland, Greenup, and South Shore.